A BRIEF INTRO ABOUT THE PICTURE PAA
HERE AMITAB SUFFERS WITH THE REAR DEADLY DISEASE OF PROGERIA.LETS KNOW WHATS GOING ON WITH PAA'S PROGERIA,,:)
Progeria (also known as "Hutchinson–Gilford progeria syndrome" and "Hutchinson–Gilford syndrome") is an extremely rare, severe, genetic condition wherein symptoms resembling aspects of aging are manifested at an early age.
The disorder has a very low incidence and occurs in one per eight million live births.Those born with progeria typically live about thirteen years, although many have been known to live into their late teens and early twenties and rare individuals may even reach their forties.
It is a genetic condition that occurs as a new mutation and is not usually inherited, although there is a uniquely inheritable form. This is in contrast to another rare but similar premature aging syndrome, dyskeratosis congenita (DKC), which is inheritable and will often be expressed multiple times in a family line.
failure to thrive and a localized scleroderma-like skin condition.
Limited growth, alopecia, and a distinctive appearance (small face and jaw, pinched nose) are all characteristic of progeria.
small, fragile bodies, like those of elderly people.
Later, the condition causes wrinkled skin, atherosclerosis, and cardiovascular problems.
childhood disorder caused by a point mutation in position 1824 of the LMNA gene, replacing cytosine with thymine, creating an unusable form of the protein Lamin A. Lamin A is part of the building blocks of the nuclear envelope.
No treatments have been proven effective. Most treatment focuses on reducing complications (such as cardiovascular disease) with heart bypass surgery or low-dose aspirin