S- EQUATIONS:
                  Ss equations are statistical equations.these are of two types
1.steady state equations
2.unsteady state equations or non steady state equations
Steady state equations:
                                 The state model where the variables are unchanging in time but where there is a net flow of mass across its boundaries is called as steady state 
And steady state cannot be affected by any external effects i.e cannot be affected by harmones.
Unsteady state equations:
                                     The state models where the variables are changing with time and unsteady state cannot be affected by any harmones
Methods to determine statistical equations:
For Steady state:
                      PBN metod is use to determine steady state equations
PBN is probability Boolean network
                     PBN  is a binary type of method where binary digits like 0 and 1 are use to determine,for every mismatch 0 is given and for every match 1 is given
For unsteady state equations:
                               There are three methods to determine unsteady type of S equations
                                 1.ordinary differential equations
                                2.partial differential equations
                                3.baysein equations
Ordinary differential equqtions: 
                                             Derived formula for ordinary differential equations for cancerous cells
          For single cancerous cells
                                     
                                           dx=γx(1-x/k)
                        Where: γ=rate of growth
                                     K=constant
                                      X=concentration of cells
                For more than one cancerous cells:
                     We use   xi,xi+1
                     
                                      dxi=γixi(1-xi/k)
      
partial differential equations:
          let us explain partial differential equations using nutrient  concentrations
                    here ‘n’ and ‘c’ depends on kd and km values 
                         where kd denotes rate of death of cells 
                                   km value denotes mass of cells
and here we can notice when nutrient concentration 
decreases death  of cells occurs.
                                 Dn=kd
For concentration of cells:dc=km+kd
Theorem for PBN type:
Given PBN value of G(v,f) with an existing state distribution,let    пy be a limiting probanility of state y. here p=0 and пy(if 0                             
                                   (пy- пy )/пy <=(1-(1-p)n)
                                    
                                                                              
   If the above equation satisfies then we can say that it is in steady state
Tuesday, February 1, 2011
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